STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ARHGEF4Rho guanine nucleotide exchange factor 4. (680 aa)    
Predicted Functional Partners:
apc2
APC regulator of WNT signaling pathway 2.
   
 0.949
apc
APC regulator of WNT signaling pathway.
   
 0.949
LOC103479675
Rac family small GTPase 2.
    
 0.945
RAC1
Rac family small GTPase 1.
    
 0.945
LOC103481975
Uncharacterized protein.
    
 0.945
LOC103456616
Spermatogenesis associated 13.
  
  
 
0.901
CDC42
Cell division cycle 42.
    
 0.774
LOC103465423
Cell division cycle 42.
    
 0.774
ywhae
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 1; Belongs to the 14-3-3 family.
    
   0.642
LOC103472837
Uncharacterized protein.
    
 0.614
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.