Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC103467068TNFR-Cys domain-containing protein. (271 aa)    
Predicted Functional Partners:
LOC103462560
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.993
LOC103477745
Tumor necrosis factor b (TNF superfamily, member 2).
   
 0.964
LOC103469572
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.964
LOC103473816
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.964
LOC103468777
TNF superfamily member 14; Belongs to the tumor necrosis factor family.
     
  0.905
ENSPREP00000020171
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
     
  0.900
tnfsf11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
    
 0.721
traf3
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.705
LOC103471589
CD40 ligand; Belongs to the tumor necrosis factor family.
    
 0.666
LOC103473320
TNF receptor-associated factor.
    
 0.657
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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