Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
vps29Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)    
Predicted Functional Partners:
vps26a
VPS26, retromer complex component A.
   
 0.999
vps35
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 0.999
ccdc93
Coiled-coil domain containing 93.
    
 
 0.988
ccdc22
Coiled-coil domain containing 22.
    
 
 0.987
LOC103476205
Uncharacterized protein.
   
 0.987
vps26b
VPS26, retromer complex component B.
   
 0.987
tbc1d5
TBC1 domain family, member 5.
    
 
 0.986
snx3
Sorting nexin 3.
   
 0.986
dennd10
DENN domain containing 10.
   
 
 0.985
commd2
COMM domain containing 2.
   
 
 0.985
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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