LOC103466417 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

LOC103466417

PRELI/MSF1 domain-containing protein. (213 aa)

Predicted Functional Partners:

triap1

0.957

prelid3b

0.669

LOC103464385

0.668

prelid3a

0.668

LOC103476593-2

0.459

tamm41

0.435

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103464385	LOC103466417	ENSPREP00000013049	ENSPREP00000008421	PRELI domain containing 3.	PRELI/MSF1 domain-containing protein.	0.668
LOC103464385	triap1	ENSPREP00000013049	ENSPREP00000009939	PRELI domain containing 3.	TP53 regulated inhibitor of apoptosis 1.	0.905
LOC103466417	LOC103464385	ENSPREP00000008421	ENSPREP00000013049	PRELI/MSF1 domain-containing protein.	PRELI domain containing 3.	0.668
LOC103466417	LOC103476593-2	ENSPREP00000008421	ENSPREP00000006013	PRELI/MSF1 domain-containing protein.	Cardiolipin synthase 1.	0.459
LOC103466417	prelid3a	ENSPREP00000008421	ENSPREP00000018810	PRELI/MSF1 domain-containing protein.	PRELI domain containing 3A.	0.668
LOC103466417	prelid3b	ENSPREP00000008421	ENSPREP00000001962	PRELI/MSF1 domain-containing protein.	PRELI/MSF1 domain-containing protein.	0.669
LOC103466417	tamm41	ENSPREP00000008421	ENSPREP00000009452	PRELI/MSF1 domain-containing protein.	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.	0.435
LOC103466417	triap1	ENSPREP00000008421	ENSPREP00000009939	PRELI/MSF1 domain-containing protein.	TP53 regulated inhibitor of apoptosis 1.	0.957
LOC103476593-2	LOC103466417	ENSPREP00000006013	ENSPREP00000008421	Cardiolipin synthase 1.	PRELI/MSF1 domain-containing protein.	0.459
LOC103476593-2	tamm41	ENSPREP00000006013	ENSPREP00000009452	Cardiolipin synthase 1.	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.	0.652
LOC103476593-2	triap1	ENSPREP00000006013	ENSPREP00000009939	Cardiolipin synthase 1.	TP53 regulated inhibitor of apoptosis 1.	0.504
prelid3a	LOC103466417	ENSPREP00000018810	ENSPREP00000008421	PRELI domain containing 3A.	PRELI/MSF1 domain-containing protein.	0.668
prelid3a	triap1	ENSPREP00000018810	ENSPREP00000009939	PRELI domain containing 3A.	TP53 regulated inhibitor of apoptosis 1.	0.905
prelid3b	LOC103466417	ENSPREP00000001962	ENSPREP00000008421	PRELI/MSF1 domain-containing protein.	PRELI/MSF1 domain-containing protein.	0.669
prelid3b	triap1	ENSPREP00000001962	ENSPREP00000009939	PRELI/MSF1 domain-containing protein.	TP53 regulated inhibitor of apoptosis 1.	0.905
tamm41	LOC103466417	ENSPREP00000009452	ENSPREP00000008421	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.	PRELI/MSF1 domain-containing protein.	0.435
tamm41	LOC103476593-2	ENSPREP00000009452	ENSPREP00000006013	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.	Cardiolipin synthase 1.	0.652
tamm41	triap1	ENSPREP00000009452	ENSPREP00000009939	Phosphatidate cytidylyltransferase, mitochondrial; Catalyzes the formation of CDP-diacylglycerol (CDP-DAG) from phosphatidic acid (PA) in the mitochondrial inner membrane. Required for the biosynthesis of the dimeric phospholipid cardiolipin, which stabilizes supercomplexes of the mitochondrial respiratory chain in the mitochondrial inner membrane.	TP53 regulated inhibitor of apoptosis 1.	0.549
triap1	LOC103464385	ENSPREP00000009939	ENSPREP00000013049	TP53 regulated inhibitor of apoptosis 1.	PRELI domain containing 3.	0.905
triap1	LOC103466417	ENSPREP00000009939	ENSPREP00000008421	TP53 regulated inhibitor of apoptosis 1.	PRELI/MSF1 domain-containing protein.	0.957

page 1 of 2

Network Stats

number of nodes:

5

number of edges:

10

average node degree:

4

avg. local clustering coefficient:

1

expected number of edges:

4

PPI enrichment p-value:

0.00533

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 105

1.55

3.39

1.74e-14

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 52

1.86

5.37

7.53e-18

GO:0019843

rRNA binding

3 of 40

1.41

0.64

0.0461

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 58

1.81

5.16

4.14e-18

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:203

Structural constituent of ribosome

7 of 14

2.23

5.39

1.40e-12

CL:118

Ribosome

11 of 65

1.76

4.68

9.30e-17

CL:120

Ribosome

9 of 60

1.71

3.81

6.98e-13

CL:123

Ribosome

8 of 55

1.7

3.43

4.43e-11

CL:206

Structural constituent of ribosome

4 of 5

2.44

3.36

3.25e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mtt03010

Ribosome

11 of 54

1.84

5.39

1.86e-18

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

8 of 38

1.86

4.06

1.26e-11

GOCC:0043232

Intracellular non-membrane-bounded organelle

9 of 131

1.37

2.23

8.13e-10

GOCC:0043229

Intracellular organelle

10 of 367

0.97

1.13

6.81e-08

GOCC:0005622

Intracellular

11 of 1182

0.5

0.43

0.00016

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 57

1.82

5.17

5.82e-18

KW-0699

rRNA-binding

3 of 38

1.43

0.86

0.0124

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (22%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About