STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LGR5Leucine rich repeat containing G protein-coupled receptor 5. (787 aa)    
Predicted Functional Partners:
rspo1
R-spondin 1.
   
 0.967
znrf3
Zinc and ring finger 3.
    
 0.962
ENSPREP00000011770
RING-type domain-containing protein.
    
 0.926
LOC103478337
R-spondin 3.
   
 0.916
ndp
Norrin cystine knot growth factor NDP.
    
 0.709
cherp
Calcium homeostasis endoplasmic reticulum protein.
    
 0.695
fzd6
Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.652
LOC103462771
Frizzled class receptor 3b; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.639
fzd3
Frizzled class receptor 3a; Belongs to the G-protein coupled receptor Fz/Smo family.
    
 0.639
lrp5
Low density lipoprotein receptor-related protein 5.
    
 0.636
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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