STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
adam23ADAM metallopeptidase domain 23. (883 aa)    
Predicted Functional Partners:
lgi3
Leucine-rich repeat LGI family, member 3.
     
 0.904
lgi2
Leucine-rich repeat LGI family, member 2b.
     
 0.866
LOC103480696
Leucine-rich repeat LGI family, member 2a.
     
 0.866
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1.
      
 0.848
ADAM11
ADAM metallopeptidase domain 11.
   
 0.696
adam22
ADAM metallopeptidase domain 22.
   
 0.696
LOC103481264
Uncharacterized protein.
   
 0.696
kansl3
KAT8 regulatory NSL complex subunit 3.
      
 0.670
LOC103474597
Uncharacterized protein.
      
 0.670
LOC103476861
Leucine-rich, glioma inactivated 1a.
     
 0.667
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (30%) [HD]