MKX protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

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[Homology]

Score

MKX

Mohawk homeobox. (292 aa)

Predicted Functional Partners:

tnmd

0.635

LOC103478374

0.596

LOC103472063

0.596

irx6

0.591

LOC103478376

0.591

hoxc4

0.554

hoxd10

0.533

meox2

0.529

hoxc9

0.527

hhex

0.505

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103472063	LOC103478376	ENSPREP00000025814	ENSPREP00000016397	Homeobox domain-containing protein.	Iroquois homeobox 4a.	0.720
LOC103472063	MKX	ENSPREP00000025814	ENSPREP00000008541	Homeobox domain-containing protein.	Mohawk homeobox.	0.596
LOC103472063	hhex	ENSPREP00000025814	ENSPREP00000004748	Homeobox domain-containing protein.	Homeobox domain-containing protein.	0.488
LOC103472063	irx6	ENSPREP00000025814	ENSPREP00000009182	Homeobox domain-containing protein.	Iroquois homeobox 6a.	0.720
LOC103478374	LOC103478376	ENSPREP00000016435	ENSPREP00000016397	Iroquois homeobox 1a.	Iroquois homeobox 4a.	0.720
LOC103478374	MKX	ENSPREP00000016435	ENSPREP00000008541	Iroquois homeobox 1a.	Mohawk homeobox.	0.596
LOC103478374	hhex	ENSPREP00000016435	ENSPREP00000004748	Iroquois homeobox 1a.	Homeobox domain-containing protein.	0.488
LOC103478374	irx6	ENSPREP00000016435	ENSPREP00000009182	Iroquois homeobox 1a.	Iroquois homeobox 6a.	0.720
LOC103478376	LOC103472063	ENSPREP00000016397	ENSPREP00000025814	Iroquois homeobox 4a.	Homeobox domain-containing protein.	0.720
LOC103478376	LOC103478374	ENSPREP00000016397	ENSPREP00000016435	Iroquois homeobox 4a.	Iroquois homeobox 1a.	0.720
LOC103478376	MKX	ENSPREP00000016397	ENSPREP00000008541	Iroquois homeobox 4a.	Mohawk homeobox.	0.591
LOC103478376	hhex	ENSPREP00000016397	ENSPREP00000004748	Iroquois homeobox 4a.	Homeobox domain-containing protein.	0.404
MKX	LOC103472063	ENSPREP00000008541	ENSPREP00000025814	Mohawk homeobox.	Homeobox domain-containing protein.	0.596
MKX	LOC103478374	ENSPREP00000008541	ENSPREP00000016435	Mohawk homeobox.	Iroquois homeobox 1a.	0.596
MKX	LOC103478376	ENSPREP00000008541	ENSPREP00000016397	Mohawk homeobox.	Iroquois homeobox 4a.	0.591
MKX	hhex	ENSPREP00000008541	ENSPREP00000004748	Mohawk homeobox.	Homeobox domain-containing protein.	0.505
MKX	hoxc4	ENSPREP00000008541	ENSPREP00000030022	Mohawk homeobox.	Homeobox C4a.	0.554
MKX	hoxc9	ENSPREP00000008541	ENSPREP00000030046	Mohawk homeobox.	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	0.527
MKX	hoxd10	ENSPREP00000008541	ENSPREP00000007830	Mohawk homeobox.	Homeobox D10a.	0.533
MKX	irx6	ENSPREP00000008541	ENSPREP00000009182	Mohawk homeobox.	Iroquois homeobox 6a.	0.591