STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103480941TIR domain-containing protein. (809 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.977
LOC103471313
Toll-like receptor 1.
  
  
0.974
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.949
tollip
Toll interacting protein.
    
 0.925
RAC1
Rac family small GTPase 1.
   
 0.914
LOC103481975
Uncharacterized protein.
   
 0.914
tlr2
TIR domain-containing protein; Belongs to the Toll-like receptor family.
  
  
 
0.901
LOC103477637
Toll-like receptor 18.
     
 
0.900
ENSPREP00000024840
TIR domain-containing protein.
   
0.723
tab2
TGF-beta activated kinase 1 (MAP3K7) binding protein 2.
    
 0.654
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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