STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEFLNeurofilament light; Belongs to the intermediate filament family. (588 aa)    
Predicted Functional Partners:
actn1
Actinin, alpha 1.
   
 0.702
actn3
Actinin alpha 3b.
   
 0.564
LOC103476717
Actinin, alpha 2b.
   
 0.564
asph
Un-named hu7910.
   
 0.514
LOC103460558
Uncharacterized protein.
   
 0.482
LOC103473962
Glutamate receptor, ionotropic, N-methyl D-aspartate 1a.
   
 0.482
trpc1
Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.
      
 0.475
pvalb
Parvalbumin 7; Belongs to the parvalbumin family.
    
 0.423
s100b
S100 calcium binding protein, beta (neural); Belongs to the S-100 family.
   
 
 0.411
ENSPREP00000000501
Tripartite motif containing 2a.
   
 0.403
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.