STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dock1Dedicator of cytokinesis 1; Belongs to the DOCK family. (1863 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.968
crk
CRK proto-oncogene, adaptor protein.
    
 0.968
ENSPREP00000023825
SH2 domain-containing protein.
    
 0.968
LOC103479675
Rac family small GTPase 2.
   
 0.951
LOC103482188
Rac family small GTPase 3b.
   
 0.951
RAC1
Rac family small GTPase 1.
   
 0.951
LOC103481975
Uncharacterized protein.
   
 0.951
bcar1
BCAR1 scaffold protein, Cas family member.
    
 0.937
bccip
Protein BCCIP homolog; Belongs to the BCP1 family.
      
 0.825
LOC103466819
Engulfment and cell motility 3.
    
 0.704
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.