LOC103468148 protein (Poecilia reticulata) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

LOC103468148

Si:ch211-195b15.7. (669 aa)

Predicted Functional Partners:

LOC103481426

0.644

ALDH18A1

0.644

LOC103458452

0.525

LOC103463549

0.525

LOC103470235

0.525

LOC103470237

0.525

gnat1

0.416

LOC103467179

0.415

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALDH18A1	LOC103468148	ENSPREP00000013516	ENSPREP00000009549	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Si:ch211-195b15.7.	0.644
ALDH18A1	LOC103481426	ENSPREP00000013516	ENSPREP00000000843	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.999
LOC103458452	LOC103468148	ENSPREP00000015705	ENSPREP00000009549	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	Si:ch211-195b15.7.	0.525
LOC103463549	LOC103468148	ENSPREP00000017763	ENSPREP00000009549	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	Si:ch211-195b15.7.	0.525
LOC103467179	LOC103468148	ENSPREP00000021938	ENSPREP00000009549	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	Si:ch211-195b15.7.	0.415
LOC103467179	gnat1	ENSPREP00000021938	ENSPREP00000005925	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.	0.935
LOC103468148	ALDH18A1	ENSPREP00000009549	ENSPREP00000013516	Si:ch211-195b15.7.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.644
LOC103468148	LOC103458452	ENSPREP00000009549	ENSPREP00000015705	Si:ch211-195b15.7.	Guanine nucleotide binding protein (G protein), alpha 11b (Gq class).	0.525
LOC103468148	LOC103463549	ENSPREP00000009549	ENSPREP00000017763	Si:ch211-195b15.7.	Guanine nucleotide binding protein (G protein), alpha 11a (Gq class).	0.525
LOC103468148	LOC103467179	ENSPREP00000009549	ENSPREP00000021938	Si:ch211-195b15.7.	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	0.415
LOC103468148	LOC103470235	ENSPREP00000009549	ENSPREP00000029602	Si:ch211-195b15.7.	Uncharacterized protein.	0.525
LOC103468148	LOC103470237	ENSPREP00000009549	ENSPREP00000029648	Si:ch211-195b15.7.	Guanine nucleotide binding protein (G protein), alpha 14a.	0.525
LOC103468148	LOC103481426	ENSPREP00000009549	ENSPREP00000000843	Si:ch211-195b15.7.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.644
LOC103468148	gnat1	ENSPREP00000009549	ENSPREP00000005925	Si:ch211-195b15.7.	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.	0.416
LOC103470235	LOC103468148	ENSPREP00000029602	ENSPREP00000009549	Uncharacterized protein.	Si:ch211-195b15.7.	0.525
LOC103470237	LOC103468148	ENSPREP00000029648	ENSPREP00000009549	Guanine nucleotide binding protein (G protein), alpha 14a.	Si:ch211-195b15.7.	0.525
LOC103481426	ALDH18A1	ENSPREP00000000843	ENSPREP00000013516	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	0.999
LOC103481426	LOC103468148	ENSPREP00000000843	ENSPREP00000009549	Delta-1-pyrroline-5-carboxylate synthase; In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.	Si:ch211-195b15.7.	0.644
gnat1	LOC103467179	ENSPREP00000005925	ENSPREP00000021938	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2.	0.935
gnat1	LOC103468148	ENSPREP00000005925	ENSPREP00000009549	Guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1.	Si:ch211-195b15.7.	0.416

Network Stats

number of nodes:

4

number of edges:

6

average node degree:

3

avg. local clustering coefficient:

1

expected number of edges:

3

PPI enrichment p-value:

0.0526

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033353

S-adenosylmethionine cycle

3 of 6

3.32

4.18

3.97e-06

GO:0006730

One-carbon metabolic process

3 of 34

2.56

2.9

0.00012

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004013

Adenosylhomocysteinase activity

3 of 3

3.62

5.1

2.79e-07

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:30809531

(2019) ITRAQ-Based Quantitative Proteomics Reveals the Proteome Profiles of Primary Duck Embryo Fibroblast Cells Infected with Duck Tembusu Virus.

3 of 15

2.92

3.43

3.13e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7158

Sulfur amino acid biosynthetic process, and Adenosylhomocysteinase-like

3 of 12

3.02

3.86

8.79e-06

CL:7161

Cysteine biosynthetic process, and Adenosylhomocysteinase-like

2 of 5

3.22

2.46

0.00067

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

apla00270

Cysteine and methionine metabolism

3 of 35

2.55

3.73

7.31e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR042172

Adenosylhomocysteinase-like superfamily

3 of 3

3.62

4.82

6.35e-07

IPR020082

S-adenosyl-L-homocysteine hydrolase, conserved site

3 of 3

3.62

4.82

6.35e-07

IPR015878

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

4.82

6.35e-07

IPR000043

Adenosylhomocysteinase-like

3 of 3

3.62

4.82

6.35e-07

IPR036291

NAD(P)-binding domain superfamily

3 of 142

1.94

1.7

0.0031

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00997

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

5.53

7.62e-08

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