LOC103482259 protein (Poecilia reticulata) - STRING interaction network

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second shell of interactors

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Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

LOC103482259

WD repeat domain 37. (500 aa)

Predicted Functional Partners:

ift140

0.711

Wdr48

0.676

mad2l1

0.658

Taf12

0.650

PACS1

0.647

LOC103459886

0.647

LOC103477281

0.647

taf10

0.645

tex10

0.632

taf2

0.630

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103459886	LOC103482259	ENSPREP00000004559	ENSPREP00000009787	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	WD repeat domain 37.	0.647
LOC103459886	Taf12	ENSPREP00000004559	ENSPREP00000007202	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
LOC103459886	taf10	ENSPREP00000004559	ENSPREP00000025580	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
LOC103459886	taf2	ENSPREP00000004559	ENSPREP00000015959	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
LOC103477281	LOC103482259	ENSPREP00000012636	ENSPREP00000009787	Uncharacterized protein.	WD repeat domain 37.	0.647
LOC103482259	LOC103459886	ENSPREP00000009787	ENSPREP00000004559	WD repeat domain 37.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.647
LOC103482259	LOC103477281	ENSPREP00000009787	ENSPREP00000012636	WD repeat domain 37.	Uncharacterized protein.	0.647
LOC103482259	PACS1	ENSPREP00000009787	ENSPREP00000003913	WD repeat domain 37.	Phosphofurin acidic cluster sorting protein 1a.	0.647
LOC103482259	Taf12	ENSPREP00000009787	ENSPREP00000007202	WD repeat domain 37.	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.650
LOC103482259	Wdr48	ENSPREP00000009787	ENSPREP00000031909	WD repeat domain 37.	WD_REPEATS_REGION domain-containing protein.	0.676
LOC103482259	ift140	ENSPREP00000009787	ENSPREP00000027530	WD repeat domain 37.	Intraflagellar transport 140 homolog (Chlamydomonas).	0.711
LOC103482259	mad2l1	ENSPREP00000009787	ENSPREP00000031986	WD repeat domain 37.	MAD2 mitotic arrest deficient-like 1 (yeast).	0.658
LOC103482259	taf10	ENSPREP00000009787	ENSPREP00000025580	WD repeat domain 37.	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.645
LOC103482259	taf2	ENSPREP00000009787	ENSPREP00000015959	WD repeat domain 37.	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.630
LOC103482259	tex10	ENSPREP00000009787	ENSPREP00000027544	WD repeat domain 37.	Testis expressed 10.	0.632
PACS1	LOC103482259	ENSPREP00000003913	ENSPREP00000009787	Phosphofurin acidic cluster sorting protein 1a.	WD repeat domain 37.	0.647
Taf12	LOC103459886	ENSPREP00000007202	ENSPREP00000004559	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
Taf12	LOC103482259	ENSPREP00000007202	ENSPREP00000009787	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	WD repeat domain 37.	0.650
Taf12	taf10	ENSPREP00000007202	ENSPREP00000025580	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999
Taf12	taf2	ENSPREP00000007202	ENSPREP00000015959	TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor.	0.999

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Network Stats

number of nodes:

11

number of edges:

37

average node degree:

6.73

avg. local clustering coefficient:

0.878

expected number of edges:

10

PPI enrichment p-value:

1.46e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 102

1.46

2.9

1.80e-13

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 56

1.72

4.42

2.05e-16

GO:0019843

rRNA binding

7 of 41

1.66

2.82

1.16e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

11 of 63

1.67

4.19

1.34e-16

GO:0044391

Ribosomal subunit

4 of 14

1.88

2.38

6.04e-06

GO:0015935

Small ribosomal subunit

2 of 6

1.95

1.21

0.0045

GO:0015934

Large ribosomal subunit

2 of 8

1.82

1.1

0.0065

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:139

Ribosome

11 of 51

1.76

4.68

8.93e-17

CL:144

Ribosome

9 of 39

1.79

4.27

1.24e-13

CL:145

rRNA-binding

6 of 31

1.71

2.8

4.47e-08

CL:196

Small ribosomal subunit, and Ribosome

3 of 5

2.2

2.11

7.99e-05

CL:231

Mixed, incl. Ribosomal L28 family, and Ribosomal protein L31

2 of 5

2.03

1.07

0.0093

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ppc03010

Ribosome

11 of 56

1.72

4.53

3.42e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

7 of 44

1.63

2.78

7.78e-09

GOCC:0043232

Intracellular non-membrane-bounded organelle

8 of 126

1.23

1.65

1.34e-07

GOCC:0043229

Intracellular organelle

11 of 281

1.02

1.3

1.86e-09

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

11 of 59

1.7

4.34

1.13e-16

KW-0699

rRNA-binding

7 of 39

1.68

3.01

2.78e-09

KW-0820

tRNA-binding

2 of 12

1.65

0.7

0.0425

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