node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LOC103472487 | LOC103473119 | ENSPREP00000018393 | ENSPREP00000017837 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.966 |
LOC103472487 | fdps | ENSPREP00000018393 | ENSPREP00000026097 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.729 |
LOC103472487 | idi1 | ENSPREP00000018393 | ENSPREP00000009858 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Isopentenyl-diphosphate delta isomerase 1. | 0.938 |
LOC103472487 | lss | ENSPREP00000018393 | ENSPREP00000001213 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.999 |
LOC103472487 | mvd | ENSPREP00000018393 | ENSPREP00000003399 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.794 |
LOC103472487 | sqle | ENSPREP00000018393 | ENSPREP00000024231 | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | Squalene epoxidase a. | 0.980 |
LOC103473119 | LOC103472487 | ENSPREP00000017837 | ENSPREP00000018393 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Cytochrome P450, family 51; Belongs to the cytochrome P450 family. | 0.966 |
LOC103473119 | coq2 | ENSPREP00000017837 | ENSPREP00000012075 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.469 |
LOC103473119 | dhdds | ENSPREP00000017837 | ENSPREP00000009591 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Alkyl transferase; Belongs to the UPP synthase family. | 0.523 |
LOC103473119 | fdps | ENSPREP00000017837 | ENSPREP00000026097 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.968 |
LOC103473119 | ggps1 | ENSPREP00000017837 | ENSPREP00000011880 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.747 |
LOC103473119 | idi1 | ENSPREP00000017837 | ENSPREP00000009858 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Isopentenyl-diphosphate delta isomerase 1. | 0.958 |
LOC103473119 | lss | ENSPREP00000017837 | ENSPREP00000001213 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. | 0.923 |
LOC103473119 | mvd | ENSPREP00000017837 | ENSPREP00000003399 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. | 0.896 |
LOC103473119 | nus1 | ENSPREP00000017837 | ENSPREP00000000913 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | NUS1 dehydrodolichyl diphosphate synthase subunit. | 0.526 |
LOC103473119 | sqle | ENSPREP00000017837 | ENSPREP00000024231 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | Squalene epoxidase a. | 0.977 |
coq2 | LOC103473119 | ENSPREP00000012075 | ENSPREP00000017837 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. | 0.469 |
coq2 | dhdds | ENSPREP00000012075 | ENSPREP00000009591 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Alkyl transferase; Belongs to the UPP synthase family. | 0.923 |
coq2 | fdps | ENSPREP00000012075 | ENSPREP00000026097 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. | 0.665 |
coq2 | ggps1 | ENSPREP00000012075 | ENSPREP00000011880 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Geranylgeranyl diphosphate synthase 1; Belongs to the FPP/GGPP synthase family. | 0.767 |