STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Wipf1WH2 domain-containing protein. (124 aa)    
Predicted Functional Partners:
LOC103472210
Sb:cb649.
    
0.912
was
WASP actin nucleation promoting factor a.
   
 0.834
wasl
WASP like actin nucleation promoting factor b.
   
 0.834
LOC103465991
WASP like actin nucleation promoting factor a.
   
 0.834
ENSPREP00000005261
Si:ch211-1o7.3.
   
 0.803
grb2
Growth factor receptor-bound protein 2b.
    
 0.763
ENSPREP00000010144
Uncharacterized protein.
 
      0.727
nck2
Cytoplasmic protein.
    
 0.636
nck1
Cytoplasmic protein.
    
 0.636
actr2
Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament.
    
 0.607
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.