STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spc25SPC25 component of NDC80 kinetochore complex. (235 aa)    
Predicted Functional Partners:
ndc80
NDC80 kinetochore complex component.
   
 0.999
nuf2
UF2 component of NDC80 kinetochore complex.
   
 0.999
spc24
SPC24 component of NDC80 kinetochore complex.
   
 0.987
mis12
MIS12 kinetochore complex component.
    
 0.954
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.952
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 
 0.927
LOC103469459
Uncharacterized protein.
   
 
 0.899
nsl1
NSL1 component of MIS12 kinetochore complex.
   
 0.898
Bub1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.888
ENSPREP00000021048
BUB1 N-terminal domain-containing protein.
   
 0.888
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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