STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pus1Pseudouridine synthase 1. (406 aa)    
Predicted Functional Partners:
wdr4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
 
 0.910
dkc1
Dyskeratosis congenita 1, dyskerin.
   
 0.863
trub1
TruB pseudouridine (psi) synthase family member 1.
   
 0.861
mrpl17
Mitochondrial ribosomal protein L17; Belongs to the bacterial ribosomal protein bL17 family.
  
  
 0.811
dus3l
tRNA-dihydrouridine(47) synthase [NAD(P)(+)].
  
 
 0.805
trub2
TruB pseudouridine (psi) synthase family member 2.
   
 0.777
mettl1
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
  
 
 0.756
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18; Belongs to the DEAD box helicase family.
  
  
 0.748
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
  
  
 0.744
polr1c
RNA polymerase I and III subunit C.
  
  
 0.744
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.