STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
znf711Zinc finger protein 711. (765 aa)    
Predicted Functional Partners:
pola1
DNA polymerase.
   
 
 0.674
dctn2
Dynactin 2 (p50).
    
 
 0.652
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.650
CYTB
Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis.
      
 0.550
prkx
Protein kinase X-linked.
   
 0.505
kdm5c
Lysine (K)-specific demethylase 5C.
   
 0.476
emsy
EMSY transcriptional repressor, BRCA2 interacting.
    
 
 0.475
LOC103475798
Lysine (K)-specific demethylase 6A, like.
   
 0.463
kdm6a
Lysine (K)-specific demethylase 6A.
   
 0.463
LOC103478912
Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family.
   
 
 0.422
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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