STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nek2NIMA-related kinase 2. (352 aa)    
Predicted Functional Partners:
bub1b
BUB1 mitotic checkpoint serine/threonine kinase Bb.
   
 0.997
cdc20
Cell division cycle 20 homolog.
   
 0.995
anapc4
Anaphase-promoting complex subunit 4; Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. Belongs to the APC4 family.
    
 0.993
cdc27
Cell division cycle 27.
    
 0.989
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.989
anapc1
Anaphase promoting complex subunit 1.
    
 0.975
LOC103479019
Fizzy/cell division cycle 20 related 1b.
   
 0.970
FZR1
Fizzy/cell division cycle 20 related 1a.
   
 0.970
Bub1
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
   
 0.960
ENSPREP00000021048
BUB1 N-terminal domain-containing protein.
   
 0.960
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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