LOC103475676 protein (Poecilia reticulata) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

LOC103475676

Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)

Predicted Functional Partners:

LOC103461092

0.727

ENSPREP00000024044

0.676

LOC103469402

0.651

ENSPREP00000017978

0.538

tpm4

0.538

LOC103469672

0.507

fgfr4

0.507

LOC103458160

0.507

ENSPREP00000013954

0.507

LOC103477293

0.507

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000013954	LOC103475676	ENSPREP00000013954	ENSPREP00000011076	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.507
ENSPREP00000017978	ENSPREP00000024044	ENSPREP00000017978	ENSPREP00000024044	Uncharacterized protein.	Uncharacterized protein.	0.728
ENSPREP00000017978	LOC103461092	ENSPREP00000017978	ENSPREP00000021625	Uncharacterized protein.	Serine/threonine/tyrosine kinase 1b.	0.526
ENSPREP00000017978	LOC103469402	ENSPREP00000017978	ENSPREP00000014515	Uncharacterized protein.	Caveolae associated protein 1a.	0.535
ENSPREP00000017978	LOC103475676	ENSPREP00000017978	ENSPREP00000011076	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.538
ENSPREP00000024044	ENSPREP00000017978	ENSPREP00000024044	ENSPREP00000017978	Uncharacterized protein.	Uncharacterized protein.	0.728
ENSPREP00000024044	LOC103461092	ENSPREP00000024044	ENSPREP00000021625	Uncharacterized protein.	Serine/threonine/tyrosine kinase 1b.	0.646
ENSPREP00000024044	LOC103469402	ENSPREP00000024044	ENSPREP00000014515	Uncharacterized protein.	Caveolae associated protein 1a.	0.646
ENSPREP00000024044	LOC103475676	ENSPREP00000024044	ENSPREP00000011076	Uncharacterized protein.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.676
ENSPREP00000024044	tpm4	ENSPREP00000024044	ENSPREP00000018680	Uncharacterized protein.	Tropomyosin 4a; Belongs to the tropomyosin family.	0.728
LOC103458160	LOC103475676	ENSPREP00000009232	ENSPREP00000011076	Fibroblast growth factor receptor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.507
LOC103461092	ENSPREP00000017978	ENSPREP00000021625	ENSPREP00000017978	Serine/threonine/tyrosine kinase 1b.	Uncharacterized protein.	0.526
LOC103461092	ENSPREP00000024044	ENSPREP00000021625	ENSPREP00000024044	Serine/threonine/tyrosine kinase 1b.	Uncharacterized protein.	0.646
LOC103461092	LOC103469402	ENSPREP00000021625	ENSPREP00000014515	Serine/threonine/tyrosine kinase 1b.	Caveolae associated protein 1a.	0.648
LOC103461092	LOC103475676	ENSPREP00000021625	ENSPREP00000011076	Serine/threonine/tyrosine kinase 1b.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.727
LOC103461092	tpm4	ENSPREP00000021625	ENSPREP00000018680	Serine/threonine/tyrosine kinase 1b.	Tropomyosin 4a; Belongs to the tropomyosin family.	0.526
LOC103469402	ENSPREP00000017978	ENSPREP00000014515	ENSPREP00000017978	Caveolae associated protein 1a.	Uncharacterized protein.	0.535
LOC103469402	ENSPREP00000024044	ENSPREP00000014515	ENSPREP00000024044	Caveolae associated protein 1a.	Uncharacterized protein.	0.646
LOC103469402	LOC103461092	ENSPREP00000014515	ENSPREP00000021625	Caveolae associated protein 1a.	Serine/threonine/tyrosine kinase 1b.	0.648
LOC103469402	LOC103475676	ENSPREP00000014515	ENSPREP00000011076	Caveolae associated protein 1a.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.651

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Network Stats

number of nodes:

11

number of edges:

35

average node degree:

6.36

avg. local clustering coefficient:

0.876

expected number of edges:

13

PPI enrichment p-value:

5.1e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

8 of 722

0.69

0.52

0.0033

GO:0016021

Integral component of membrane

8 of 1042

0.53

0.37

0.0168

GO:0016020

Membrane

9 of 1458

0.44

0.32

0.0168

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4236

Diguanylate cyclase

6 of 38

1.85

3.03

5.65e-08

CL:4239

EAL domain, and PAS-associated, C-terminal

5 of 33

1.83

2.56

1.23e-06

CL:4058

Phosphorelay signal transduction system, and Nucleotide cyclase

9 of 144

1.45

2.43

1.19e-09

CL:4243

EAL domain, and Target SNARE coiled-coil homology domain

4 of 19

1.97

2.32

1.38e-05

CL:4245

EAL domain, and Target SNARE coiled-coil homology domain

3 of 12

2.05

1.73

0.00039

(more ...)

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR029787

Nucleotide cyclase

6 of 61

1.64

2.15

4.06e-06

IPR000160

GGDEF domain

6 of 62

1.64

2.14

4.06e-06

IPR043128

Reverse transcriptase/Diguanylate cyclase domain

6 of 65

1.61

2.11

4.06e-06

IPR001633

EAL domain

4 of 30

1.77

1.66

0.00028

IPR035919

EAL domain superfamily

4 of 31

1.76

1.65

0.00028

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00267

Diguanylate cyclase

6 of 57

1.67

2.54

2.13e-07

SM00052

Putative diguanylate phosphodiesterase

4 of 30

1.77

1.97

4.24e-05

SM00091

PAS domain

3 of 42

1.5

1.03

0.0052

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