STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rcn3Reticulocalbin 3, EF-hand calcium binding domain. (301 aa)    
Predicted Functional Partners:
LOC103465792
RIC8 guanine nucleotide exchange factor A.
     
 0.656
LOC103468147
Proline rich Gla (G-carboxyglutamic acid) 2.
      
 0.643
nosip
Nitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing nitric oxide synthase translocation to actin cytoskeleton and inhibiting its enzymatic activity; Belongs to the NOSIP family.
      
 0.636
immp1l
Mitochondrial inner membrane protease subunit.
      
 0.636
eif3m
Eukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.
   
  
 0.557
elp4
Elongator acetyltransferase complex subunit 4.
      
 0.550
mapk7
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
      
 0.529
crtap
Cartilage associated protein.
   
 
 0.504
LOC103469251
FAM20C golgi associated secretory pathway kinase a.
    
  0.496
dnajc24
Uncharacterized protein.
    
 0.492
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.