STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Grb14Uncharacterized protein. (199 aa)    
Predicted Functional Partners:
ENSPREP00000011332
SH2 domain-containing protein.
 
      0.900
grb2
Growth factor receptor-bound protein 2b.
    
 0.540
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.537
LOC103466654
Tyrosine-protein kinase receptor.
    
 0.534
LOC103462605
Tyrosine-protein kinase receptor.
    
 0.534
insr
Insulin receptor a.
    
 0.534
ENSPREP00000025003
Uncharacterized protein.
    
 0.534
tie1
Tyrosine kinase with immunoglobulin-like and EGF-like domains 1.
   
  0.505
ENSPREP00000009325
GRB2 related adaptor protein b.
    
 0.490
ENSPREP00000009358
Uncharacterized protein.
    
 0.490
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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