STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kpna3Importin subunit alpha; Belongs to the importin alpha family. (521 aa)    
Predicted Functional Partners:
cse1l
CSE1 chromosome segregation 1-like (yeast).
   
 0.973
LOC103480184
V-rel avian reticuloendotheliosis viral oncogene homolog A.
    
 0.931
kpna1
Importin subunit alpha; Belongs to the importin alpha family.
  
0.926
kpna4
Importin subunit alpha; Belongs to the importin alpha family.
  
  
 
0.900
kpnb1
Karyopherin (importin) beta 1.
   
 0.875
rcc1
Regulator of chromosome condensation 1.
   
 
 0.847
LOC103461037
RAN binding protein 2.
   
 
 0.756
nup153
Nucleoporin 153.
   
 
 0.676
ncbp2
Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]
   
 
 0.675
NCBP1
Nuclear cap binding protein subunit 1.
   
 
 0.674
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.