STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gcgGlucagon b. (115 aa)    
Predicted Functional Partners:
LOC103476384
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.728
ENSPREP00000030771
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.728
gcgr
Glucagon receptor a; Belongs to the G-protein coupled receptor 2 family.
    
 0.703
LOC103473485
Glucagon receptor b; Belongs to the G-protein coupled receptor 2 family.
    
 0.651
ada
Adenosine deaminase.
   
 
 0.638
GPR119
G protein-coupled receptor 119; Belongs to the G-protein coupled receptor 1 family.
     
 0.594
GLP2R
Glucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.585
ENSPREP00000027198
Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family.
    
 0.562
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 
 0.557
sec11a
Signal peptidase complex catalytic subunit SEC11.
   
 
 0.522
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.