STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
leng8Leukocyte receptor cluster (LRC) member 8. (760 aa)    
Predicted Functional Partners:
Pcid2
PCI domain-containing protein.
   
 
 0.959
ENSPREP00000002977
SEM1 26S proteasome complex subunit.
    
 
 0.904
fnbp4
Formin binding protein 4.
   
  
 0.566
Cdc42ep5
CDC42 effector protein (Rho GTPase binding) 5.
      
 0.561
ilvbl
IlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family.
      
 0.549
snapc4
Uncharacterized protein.
   
    0.523
dffb
DNA fragmentation factor, beta polypeptide (caspase-activated DNase).
   
  
 0.483
ENSPREP00000020113
CULLIN_2 domain-containing protein; Belongs to the cullin family.
   
    0.451
ENSPREP00000020124
Uncharacterized protein.
   
    0.451
med18
Mediator of RNA polymerase II transcription subunit 18; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
      
 0.443
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.