ENSPREP00000011965 protein (Poecilia reticulata)

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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protein homology

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Score

ENSPREP00000011965

G_PROTEIN_RECEP_F1_2 domain-containing protein. (356 aa)

Predicted Functional Partners:

gal

0.984

ENSPREP00000017976

0.614

rxfp2

0.514

LOC103464554

0.487

pnoc

0.479

POMC

0.479

LOC103472811

0.479

LOC103475296

0.477

penk

0.466

apln

0.456

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000011965	ENSPREP00000017976	ENSPREP00000011965	ENSPREP00000017976	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Spexin hormone.	0.614
ENSPREP00000011965	LOC103464554	ENSPREP00000011965	ENSPREP00000005189	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.487
ENSPREP00000011965	LOC103472811	ENSPREP00000011965	ENSPREP00000031135	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.479
ENSPREP00000011965	LOC103475296	ENSPREP00000011965	ENSPREP00000004434	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Somatostatin.	0.477
ENSPREP00000011965	POMC	ENSPREP00000011965	ENSPREP00000019746	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Proopiomelanocortin.	0.479
ENSPREP00000011965	apln	ENSPREP00000011965	ENSPREP00000017384	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Apelin.	0.456
ENSPREP00000011965	gal	ENSPREP00000011965	ENSPREP00000009414	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Galanin/GMAP prepropeptide.	0.984
ENSPREP00000011965	penk	ENSPREP00000011965	ENSPREP00000017744	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Uncharacterized protein.	0.466
ENSPREP00000011965	pnoc	ENSPREP00000011965	ENSPREP00000006743	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Prepronociceptin a.	0.479
ENSPREP00000011965	rxfp2	ENSPREP00000011965	ENSPREP00000015587	G_PROTEIN_RECEP_F1_2 domain-containing protein.	Relaxin family peptide receptor 2a.	0.514
ENSPREP00000017976	ENSPREP00000011965	ENSPREP00000017976	ENSPREP00000011965	Spexin hormone.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.614
ENSPREP00000017976	gal	ENSPREP00000017976	ENSPREP00000009414	Spexin hormone.	Galanin/GMAP prepropeptide.	0.468
LOC103464554	ENSPREP00000011965	ENSPREP00000005189	ENSPREP00000011965	Oxytocin receptor like; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.487
LOC103472811	ENSPREP00000011965	ENSPREP00000031135	ENSPREP00000011965	Uncharacterized protein.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.479
LOC103472811	LOC103475296	ENSPREP00000031135	ENSPREP00000004434	Uncharacterized protein.	Somatostatin.	0.711
LOC103472811	apln	ENSPREP00000031135	ENSPREP00000017384	Uncharacterized protein.	Apelin.	0.699
LOC103472811	gal	ENSPREP00000031135	ENSPREP00000009414	Uncharacterized protein.	Galanin/GMAP prepropeptide.	0.672
LOC103472811	penk	ENSPREP00000031135	ENSPREP00000017744	Uncharacterized protein.	Uncharacterized protein.	0.965
LOC103472811	pnoc	ENSPREP00000031135	ENSPREP00000006743	Uncharacterized protein.	Prepronociceptin a.	0.965
LOC103475296	ENSPREP00000011965	ENSPREP00000004434	ENSPREP00000011965	Somatostatin.	G_PROTEIN_RECEP_F1_2 domain-containing protein.	0.477

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.893

expected number of edges:

13

PPI enrichment p-value:

0.0498

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019321

Pentose metabolic process

5 of 6

2.21

3.09

5.79e-07

GO:0019323

Pentose catabolic process

4 of 5

2.2

2.35

2.44e-05

GO:0016052

Carbohydrate catabolic process

5 of 48

1.31

1.2

0.00054

GO:0042732

D-xylose metabolic process

2 of 2

2.29

0.96

0.0170

GO:0005975

Carbohydrate metabolic process

7 of 150

0.96

0.84

0.00052

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:25138599

(2014) Crystal structure of Talaromyces cellulolyticus (formerly known as Acremonium cellulolyticus) GH family 11 xylanase.

2 of 2

2.29

1.08

0.0098

PMID:25024744

(2014) Zymomonas mobilis: a novel platform for future biorefineries.

2 of 2

2.29

1.08

0.0098

PMID:24949262

(2014) Xylanase (GH11) from Acremonium cellulolyticus: homologous expression and characterization.

2 of 4

1.99

1.05

0.0098

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1471

Pentose metabolic process, and 6-phosphogluconate dehydrogenase, domain 2

6 of 11

2.03

3.48

1.99e-08

CL:1472

Pentose metabolic process

5 of 6

2.21

3.37

1.35e-07

CL:1198

Mixed, incl. Carbon metabolism, and Fatty acid metabolic process

7 of 149

0.96

0.86

0.00038

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

ace00040

Pentose and glucuronate interconversions

7 of 15

1.96

4.08

1.27e-10

ace00051

Fructose and mannose metabolism

3 of 19

1.49

0.97

0.0072

ace01100

Metabolic pathways

8 of 510

0.49

0.33

0.0283

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0119

Carbohydrate metabolism

4 of 23

1.53

1.27

0.0012

KW-0859

Xylose metabolism

2 of 2

2.29

1.0

0.0140

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02782

FGGY family of carbohydrate kinases, C-terminal domain

3 of 3

2.29

1.67

0.00071

PF00370

FGGY family of carbohydrate kinases, N-terminal domain

3 of 3

2.29

1.67

0.00071

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR018485

Carbohydrate kinase, FGGY, C-terminal

3 of 3

2.29

1.43

0.0021

IPR018484

Carbohydrate kinase, FGGY, N-terminal

3 of 3

2.29

1.43

0.0021

IPR000577

Carbohydrate kinase, FGGY

3 of 3

2.29

1.43

0.0021

IPR043129

ATPase, nucleotide binding domain

3 of 18

1.51

0.72

0.0336

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