STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlxH2.0-like homeo box 1 (Drosophila). (522 aa)    
Predicted Functional Partners:
ARHGEF2
Rho/rac guanine nucleotide exchange factor (GEF) 2.
   
  
 0.631
znf148
Zinc finger protein 148.
   
 
 0.610
LOC103457369
Akirin 2.
      
 0.606
AKIRIN2
Akirin 2.
      
 0.606
LOC103479675
Rac family small GTPase 2.
   
 0.601
dhx58
DEXH (Asp-Glu-X-His) box polypeptide 58.
      
 0.597
PRKCA
Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.
      
 0.594
lck
Tyrosine-protein kinase.
    
 
 0.594
pde4b
Phosphodiesterase.
      
 0.594
LOC103478918
Tyrosine-protein kinase.
    
 
 0.593
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.