STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000011981LTO1 maturation factor of ABCE1. (140 aa)    
Predicted Functional Partners:
yae1
OTU deubiquitinase with linear linkage specificity a.
   
 
 0.844
ENSPREP00000003924
ATP-binding cassette, sub-family E (OABP), member 1.
    
 
 0.836
LOC103463013
PTPRF interacting protein alpha 1.
      
 0.523
mtch2
Mitochondrial carrier homolog 2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
      
 0.523
mms19
MMS19 homolog, cytosolic iron-sulfur assembly component.
    
 
 0.470
fgf19
Fibroblast growth factor 19; Belongs to the heparin-binding growth factors family.
      
 0.440
iba57
Iron-sulfur cluster assembly factor IBA57.
      
 0.408
ciapin1
Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...]
      
 0.406
mettl25
Methyltransferase like 25.
   
  
 0.402
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.