STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
axin1Axin 1. (850 aa)    
Predicted Functional Partners:
ctnnb1
Catenin (cadherin-associated protein), beta 1.
   
 0.988
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
    
 0.987
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate a; Belongs to the protein kinase superfamily.
   
 0.984
apc2
APC regulator of WNT signaling pathway 2.
   
 0.980
apc
APC regulator of WNT signaling pathway.
   
 0.980
LOC103472282
Uncharacterized protein.
   
 0.975
dvl2
Dishevelled segment polarity protein 2.
   
0.970
ENSPREP00000001242
DIX domain-containing protein.
   
 0.963
ENSPREP00000020826
DIX domain-containing protein.
   
 0.963
LOC103468446
Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.
    
 0.948
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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