STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zfand1Zinc finger, AN1-type domain 1. (269 aa)    
Predicted Functional Partners:
LOC103482061
Zgc:136908; Belongs to the AAA ATPase family.
    
 
 0.657
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
    
 
 0.657
SPATA5
Spermatogenesis associated 5.
    
 
 0.616
spata5l1
Spermatogenesis associated 5-like 1.
    
 
 0.616
uba52
Ubiquitin A-52 residue ribosomal protein fusion product 1.
   
 
 0.605
psmd1
26S proteasome non-ATPase regulatory subunit 1; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S1 family.
    
 
 0.561
rps27a
Ribosomal protein S27a.
    
 
 0.537
nsfl1c
NSFL1 (p97) cofactor (p47).
    
   0.521
zfand4
Zinc finger, AN1-type domain 4.
    
 
 0.507
Katnal2
Katanin p60 subunit A-like 2.
   
 
 0.503
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.