LOC103472997 protein (Poecilia reticulata) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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protein homology

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[Homology]

Score

LOC103472997

MYC binding protein. (168 aa)

Predicted Functional Partners:

lrguk

0.816

yars1

0.681

mycbpap

0.674

LOC103465147

0.630

spen

0.630

ENSPREP00000027150

0.625

pgk1

0.596

znf746

0.536

polr3e

0.526

cfap69

0.487

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000027150	LOC103472997	ENSPREP00000027150	ENSPREP00000012321	Uncharacterized protein.	MYC binding protein.	0.625
ENSPREP00000027150	mycbpap	ENSPREP00000027150	ENSPREP00000000472	Uncharacterized protein.	Mycbp associated protein.	0.716
ENSPREP00000027150	pgk1	ENSPREP00000027150	ENSPREP00000008812	Uncharacterized protein.	Phosphoglycerate kinase.	0.716
LOC103465147	LOC103472997	ENSPREP00000007862	ENSPREP00000012321	Si:ch1073-335m2.2.	MYC binding protein.	0.630
LOC103465147	znf746	ENSPREP00000007862	ENSPREP00000013282	Si:ch1073-335m2.2.	Kruppel-like factor 13.	0.484
LOC103472997	ENSPREP00000027150	ENSPREP00000012321	ENSPREP00000027150	MYC binding protein.	Uncharacterized protein.	0.625
LOC103472997	LOC103465147	ENSPREP00000012321	ENSPREP00000007862	MYC binding protein.	Si:ch1073-335m2.2.	0.630
LOC103472997	cfap69	ENSPREP00000012321	ENSPREP00000012684	MYC binding protein.	Uncharacterized protein.	0.487
LOC103472997	lrguk	ENSPREP00000012321	ENSPREP00000005226	MYC binding protein.	Leucine-rich repeats and guanylate kinase domain containing.	0.816
LOC103472997	mycbpap	ENSPREP00000012321	ENSPREP00000000472	MYC binding protein.	Mycbp associated protein.	0.674
LOC103472997	pgk1	ENSPREP00000012321	ENSPREP00000008812	MYC binding protein.	Phosphoglycerate kinase.	0.596
LOC103472997	polr3e	ENSPREP00000012321	ENSPREP00000005929	MYC binding protein.	Polymerase (RNA) III (DNA directed) polypeptide E.	0.526
LOC103472997	spen	ENSPREP00000012321	ENSPREP00000015415	MYC binding protein.	Spen family transcriptional repressor.	0.630
LOC103472997	yars1	ENSPREP00000012321	ENSPREP00000027064	MYC binding protein.	Tyrosine--tRNA ligase.	0.681
LOC103472997	znf746	ENSPREP00000012321	ENSPREP00000013282	MYC binding protein.	Kruppel-like factor 13.	0.536
cfap69	LOC103472997	ENSPREP00000012684	ENSPREP00000012321	Uncharacterized protein.	MYC binding protein.	0.487
cfap69	lrguk	ENSPREP00000012684	ENSPREP00000005226	Uncharacterized protein.	Leucine-rich repeats and guanylate kinase domain containing.	0.821
lrguk	LOC103472997	ENSPREP00000005226	ENSPREP00000012321	Leucine-rich repeats and guanylate kinase domain containing.	MYC binding protein.	0.816
lrguk	cfap69	ENSPREP00000005226	ENSPREP00000012684	Leucine-rich repeats and guanylate kinase domain containing.	Uncharacterized protein.	0.821
mycbpap	ENSPREP00000027150	ENSPREP00000000472	ENSPREP00000027150	Mycbp associated protein.	Uncharacterized protein.	0.716

page 1 of 2

Network Stats

number of nodes:

4

number of edges:

6

average node degree:

3

avg. local clustering coefficient:

1

expected number of edges:

3

PPI enrichment p-value:

0.0526

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0033353

S-adenosylmethionine cycle

3 of 6

3.32

4.18

3.97e-06

GO:0006730

One-carbon metabolic process

3 of 34

2.56

2.9

0.00012

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004013

Adenosylhomocysteinase activity

3 of 3

3.62

5.1

2.79e-07

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:30809531

(2019) ITRAQ-Based Quantitative Proteomics Reveals the Proteome Profiles of Primary Duck Embryo Fibroblast Cells Infected with Duck Tembusu Virus.

3 of 15

2.92

3.43

3.13e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:7158

Sulfur amino acid biosynthetic process, and Adenosylhomocysteinase-like

3 of 12

3.02

3.86

8.79e-06

CL:7161

Cysteine biosynthetic process, and Adenosylhomocysteinase-like

2 of 5

3.22

2.46

0.00067

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

apla00270

Cysteine and methionine metabolism

3 of 35

2.55

3.73

7.31e-06

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR042172

Adenosylhomocysteinase-like superfamily

3 of 3

3.62

4.82

6.35e-07

IPR020082

S-adenosyl-L-homocysteine hydrolase, conserved site

3 of 3

3.62

4.82

6.35e-07

IPR015878

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

4.82

6.35e-07

IPR000043

Adenosylhomocysteinase-like

3 of 3

3.62

4.82

6.35e-07

IPR036291

NAD(P)-binding domain superfamily

3 of 142

1.94

1.7

0.0031

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00997

S-adenosyl-L-homocysteine hydrolase, NAD binding domain

3 of 3

3.62

5.53

7.62e-08

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