STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000012416Serologically defined colon cancer antigen 8. (456 aa)    
Predicted Functional Partners:
PLK1
Serine/threonine-protein kinase PLK.
   
 0.693
plk3
Serine/threonine-protein kinase PLK.
   
 0.693
plk2
Serine/threonine-protein kinase PLK.
   
 0.693
bora
Bora aurora kinase A activator.
   
 
 0.596
ENSPREP00000011091
Coiled-coil domain containing 13.
    
 
 0.474
CEP164
Centrosomal protein 164.
   
 0.463
aurka
Aurora kinase A; Belongs to the protein kinase superfamily.
   
 0.444
LOC103471497
Aurora kinase B; Belongs to the protein kinase superfamily.
   
 0.444
bbs1
Bardet-Biedl syndrome 1.
   
 
 0.440
cep126
Uncharacterized protein.
    
 0.439
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.