STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103481609Growth factor receptor bound protein 7. (525 aa)    
Predicted Functional Partners:
crkl
V-crk avian sarcoma virus CT10 oncogene homolog-like.
    
 0.689
vav2
Vav 2 guanine nucleotide exchange factor.
   
 
 0.665
VAV3
Vav guanine nucleotide exchange factor 3.
   
 
 0.567
ephb4
Eph receptor B4a.
    
 0.543
grb2
Growth factor receptor-bound protein 2b.
    
0.540
ret
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.537
ephb1
EPH receptor B1.
    
 0.537
LOC103463084
Uncharacterized protein.
    
 0.537
LOC103466654
Tyrosine-protein kinase receptor.
    
 0.534
LOC103462605
Tyrosine-protein kinase receptor.
    
 0.534
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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