icmt protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

icmt

Protein-S-isoprenylcysteine O-methyltransferase. (291 aa)

Predicted Functional Partners:

zmpste24

0.964

fnta

0.650

rce1

0.595

ENSPREP00000010801

0.595

tbccd1

0.575

rcc1

0.562

rala

0.554

CSDE1

0.554

LOC103456799

0.554

LOC103469088

0.554

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	ENSPREP00000010801	ENSPREP00000017340	ENSPREP00000010801	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein.	0.478
CSDE1	fnta	ENSPREP00000017340	ENSPREP00000005785	Cold shock domain containing E1, RNA-binding.	Farnesyltransferase, CAAX box, alpha.	0.533
CSDE1	icmt	ENSPREP00000017340	ENSPREP00000012730	Cold shock domain containing E1, RNA-binding.	Protein-S-isoprenylcysteine O-methyltransferase.	0.554
CSDE1	rce1	ENSPREP00000017340	ENSPREP00000004198	Cold shock domain containing E1, RNA-binding.	Ras converting CAAX endopeptidase 1a.	0.478
ENSPREP00000010801	CSDE1	ENSPREP00000010801	ENSPREP00000017340	Uncharacterized protein.	Cold shock domain containing E1, RNA-binding.	0.478
ENSPREP00000010801	LOC103456799	ENSPREP00000010801	ENSPREP00000019487	Uncharacterized protein.	Uncharacterized protein.	0.475
ENSPREP00000010801	LOC103469088	ENSPREP00000010801	ENSPREP00000020359	Uncharacterized protein.	Zgc:55558.	0.478
ENSPREP00000010801	fnta	ENSPREP00000010801	ENSPREP00000005785	Uncharacterized protein.	Farnesyltransferase, CAAX box, alpha.	0.791
ENSPREP00000010801	icmt	ENSPREP00000010801	ENSPREP00000012730	Uncharacterized protein.	Protein-S-isoprenylcysteine O-methyltransferase.	0.595
ENSPREP00000010801	rala	ENSPREP00000010801	ENSPREP00000002768	Uncharacterized protein.	V-ral simian leukemia viral oncogene homolog Aa (ras related).	0.475
ENSPREP00000010801	zmpste24	ENSPREP00000010801	ENSPREP00000029824	Uncharacterized protein.	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family.	0.757
LOC103456799	ENSPREP00000010801	ENSPREP00000019487	ENSPREP00000010801	Uncharacterized protein.	Uncharacterized protein.	0.475
LOC103456799	fnta	ENSPREP00000019487	ENSPREP00000005785	Uncharacterized protein.	Farnesyltransferase, CAAX box, alpha.	0.533
LOC103456799	icmt	ENSPREP00000019487	ENSPREP00000012730	Uncharacterized protein.	Protein-S-isoprenylcysteine O-methyltransferase.	0.554
LOC103456799	rce1	ENSPREP00000019487	ENSPREP00000004198	Uncharacterized protein.	Ras converting CAAX endopeptidase 1a.	0.475
LOC103469088	ENSPREP00000010801	ENSPREP00000020359	ENSPREP00000010801	Zgc:55558.	Uncharacterized protein.	0.478
LOC103469088	fnta	ENSPREP00000020359	ENSPREP00000005785	Zgc:55558.	Farnesyltransferase, CAAX box, alpha.	0.533
LOC103469088	icmt	ENSPREP00000020359	ENSPREP00000012730	Zgc:55558.	Protein-S-isoprenylcysteine O-methyltransferase.	0.554
LOC103469088	rce1	ENSPREP00000020359	ENSPREP00000004198	Zgc:55558.	Ras converting CAAX endopeptidase 1a.	0.478
fnta	CSDE1	ENSPREP00000005785	ENSPREP00000017340	Farnesyltransferase, CAAX box, alpha.	Cold shock domain containing E1, RNA-binding.	0.533