dut protein (Poecilia reticulata) - STRING interaction network

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Predicted Interactions

gene neighborhood

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Score

dut

Deoxyuridine triphosphatase. (200 aa)

Predicted Functional Partners:

tyms

0.990

dtymk

0.971

dctd

0.969

tk1

0.967

itpa

0.946

tk2

0.946

nme6

0.946

cmpk1

0.945

LOC103482172

0.941

LOC103469013

0.941

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC103469013	LOC103482172	ENSPREP00000017608	ENSPREP00000006159	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.901
LOC103469013	cmpk1	ENSPREP00000017608	ENSPREP00000010242	NDK domain-containing protein; Belongs to the NDK family.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.939
LOC103469013	dtymk	ENSPREP00000017608	ENSPREP00000021619	NDK domain-containing protein; Belongs to the NDK family.	Deoxythymidylate kinase (thymidylate kinase).	0.954
LOC103469013	dut	ENSPREP00000017608	ENSPREP00000012958	NDK domain-containing protein; Belongs to the NDK family.	Deoxyuridine triphosphatase.	0.941
LOC103469013	itpa	ENSPREP00000017608	ENSPREP00000001180	NDK domain-containing protein; Belongs to the NDK family.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.961
LOC103469013	nme6	ENSPREP00000017608	ENSPREP00000028503	NDK domain-containing protein; Belongs to the NDK family.	Nucleoside diphosphate kinase.	0.921
LOC103482172	LOC103469013	ENSPREP00000006159	ENSPREP00000017608	Nucleoside diphosphate kinase.	NDK domain-containing protein; Belongs to the NDK family.	0.901
LOC103482172	cmpk1	ENSPREP00000006159	ENSPREP00000010242	Nucleoside diphosphate kinase.	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	0.939
LOC103482172	dtymk	ENSPREP00000006159	ENSPREP00000021619	Nucleoside diphosphate kinase.	Deoxythymidylate kinase (thymidylate kinase).	0.954
LOC103482172	dut	ENSPREP00000006159	ENSPREP00000012958	Nucleoside diphosphate kinase.	Deoxyuridine triphosphatase.	0.941
LOC103482172	itpa	ENSPREP00000006159	ENSPREP00000001180	Nucleoside diphosphate kinase.	Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions; Belongs to the HAM1 NTPase family.	0.961
LOC103482172	nme6	ENSPREP00000006159	ENSPREP00000028503	Nucleoside diphosphate kinase.	Nucleoside diphosphate kinase.	0.918
cmpk1	LOC103469013	ENSPREP00000010242	ENSPREP00000017608	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	NDK domain-containing protein; Belongs to the NDK family.	0.939
cmpk1	LOC103482172	ENSPREP00000010242	ENSPREP00000006159	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.939
cmpk1	dctd	ENSPREP00000010242	ENSPREP00000032810	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	dCMP deaminase.	0.918
cmpk1	dtymk	ENSPREP00000010242	ENSPREP00000021619	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxythymidylate kinase (thymidylate kinase).	0.713
cmpk1	dut	ENSPREP00000010242	ENSPREP00000012958	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Deoxyuridine triphosphatase.	0.945
cmpk1	nme6	ENSPREP00000010242	ENSPREP00000028503	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Nucleoside diphosphate kinase.	0.939
cmpk1	tk1	ENSPREP00000010242	ENSPREP00000000585	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidine kinase.	0.926
cmpk1	tk2	ENSPREP00000010242	ENSPREP00000011558	UMP-CMP kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity; Belongs to the adenylate kinase family. UMP-CMP kinase subfamily.	Thymidine kinase 2.	0.933