rfx2 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

rfx2

Regulatory factor X, 2 (influences HLA class II expression). (502 aa)

Predicted Functional Partners:

atr

0.789

LOC103481016

0.647

chek2

0.609

ENSPREP00000016558

0.529

arl13b

0.495

rfxap

0.476

dync2li1

0.473

rfxank

0.426

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000016558	rfx2	ENSPREP00000016558	ENSPREP00000013003	Fork-head domain-containing protein.	Regulatory factor X, 2 (influences HLA class II expression).	0.529
LOC103481016	rfx2	ENSPREP00000024326	ENSPREP00000013003	Forkhead box J1b.	Regulatory factor X, 2 (influences HLA class II expression).	0.647
arl13b	rfx2	ENSPREP00000009259	ENSPREP00000013003	ADP-ribosylation factor-like 13b.	Regulatory factor X, 2 (influences HLA class II expression).	0.495
atr	chek2	ENSPREP00000016955	ENSPREP00000024020	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Checkpoint kinase 2.	0.995
atr	rfx2	ENSPREP00000016955	ENSPREP00000013003	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	Regulatory factor X, 2 (influences HLA class II expression).	0.789
chek2	atr	ENSPREP00000024020	ENSPREP00000016955	Checkpoint kinase 2.	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.995
chek2	rfx2	ENSPREP00000024020	ENSPREP00000013003	Checkpoint kinase 2.	Regulatory factor X, 2 (influences HLA class II expression).	0.609
dync2li1	rfx2	ENSPREP00000005485	ENSPREP00000013003	Dynein, cytoplasmic 2, light intermediate chain 1.	Regulatory factor X, 2 (influences HLA class II expression).	0.473
rfx2	ENSPREP00000016558	ENSPREP00000013003	ENSPREP00000016558	Regulatory factor X, 2 (influences HLA class II expression).	Fork-head domain-containing protein.	0.529
rfx2	LOC103481016	ENSPREP00000013003	ENSPREP00000024326	Regulatory factor X, 2 (influences HLA class II expression).	Forkhead box J1b.	0.647
rfx2	arl13b	ENSPREP00000013003	ENSPREP00000009259	Regulatory factor X, 2 (influences HLA class II expression).	ADP-ribosylation factor-like 13b.	0.495
rfx2	atr	ENSPREP00000013003	ENSPREP00000016955	Regulatory factor X, 2 (influences HLA class II expression).	ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.	0.789
rfx2	chek2	ENSPREP00000013003	ENSPREP00000024020	Regulatory factor X, 2 (influences HLA class II expression).	Checkpoint kinase 2.	0.609
rfx2	dync2li1	ENSPREP00000013003	ENSPREP00000005485	Regulatory factor X, 2 (influences HLA class II expression).	Dynein, cytoplasmic 2, light intermediate chain 1.	0.473
rfx2	rfxank	ENSPREP00000013003	ENSPREP00000010168	Regulatory factor X, 2 (influences HLA class II expression).	Regulatory factor X-associated ankyrin-containing protein.	0.426
rfx2	rfxap	ENSPREP00000013003	ENSPREP00000017037	Regulatory factor X, 2 (influences HLA class II expression).	Regulatory factor X-associated protein.	0.476
rfxank	rfx2	ENSPREP00000010168	ENSPREP00000013003	Regulatory factor X-associated ankyrin-containing protein.	Regulatory factor X, 2 (influences HLA class II expression).	0.426
rfxank	rfxap	ENSPREP00000010168	ENSPREP00000017037	Regulatory factor X-associated ankyrin-containing protein.	Regulatory factor X-associated protein.	0.851
rfxap	rfx2	ENSPREP00000017037	ENSPREP00000013003	Regulatory factor X-associated protein.	Regulatory factor X, 2 (influences HLA class II expression).	0.476
rfxap	rfxank	ENSPREP00000017037	ENSPREP00000010168	Regulatory factor X-associated protein.	Regulatory factor X-associated ankyrin-containing protein.	0.851