STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nom1Nucleolar protein with MIF4G domain 1. (830 aa)    
Predicted Functional Partners:
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
   
 
 0.985
ddx10
RNA helicase.
   
 
 0.985
LOC103482313
Neuroguidin, EIF4E binding protein.
   
   0.982
krr1
KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly.
   
 
 0.980
utp3
UTP3 small subunit processome component.
   
 
 0.976
nat10
RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation.
   
 
 0.972
rrp36
Ribosomal RNA processing 36.
   
 
 0.972
esf1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae).
   
   0.969
noc4l
Nucleolar complex associated 4 homolog.
   
   0.968
rrp9
Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein.
   
   0.966
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.