gpn1 protein (Poecilia reticulata) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

gpn1

GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import. (431 aa)

Predicted Functional Partners:

gpn2

0.958

rpap2

0.951

gpn3

0.948

polr2b

0.945

polr2c

0.922

polr2a

0.909

POLR2E

0.890

polr2g

0.884

polr1c

0.852

polr2j

0.838

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
POLR2E	gpn1	ENSPREP00000009571	ENSPREP00000013283	RNA polymerase II subunit E.	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	0.890
POLR2E	gpn3	ENSPREP00000009571	ENSPREP00000010255	RNA polymerase II subunit E.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.745
POLR2E	polr1c	ENSPREP00000009571	ENSPREP00000011742	RNA polymerase II subunit E.	RNA polymerase I and III subunit C.	0.999
POLR2E	polr2a	ENSPREP00000009571	ENSPREP00000019508	RNA polymerase II subunit E.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
POLR2E	polr2b	ENSPREP00000009571	ENSPREP00000016486	RNA polymerase II subunit E.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.999
POLR2E	polr2c	ENSPREP00000009571	ENSPREP00000004397	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.999
POLR2E	polr2g	ENSPREP00000009571	ENSPREP00000024621	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.999
POLR2E	polr2j	ENSPREP00000009571	ENSPREP00000022590	RNA polymerase II subunit E.	Polymerase (RNA) II (DNA directed) polypeptide J.	0.999
POLR2E	rpap2	ENSPREP00000009571	ENSPREP00000011719	RNA polymerase II subunit E.	RNA polymerase II associated protein 2.	0.972
gpn1	POLR2E	ENSPREP00000013283	ENSPREP00000009571	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	RNA polymerase II subunit E.	0.890
gpn1	gpn2	ENSPREP00000013283	ENSPREP00000013035	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.958
gpn1	gpn3	ENSPREP00000013283	ENSPREP00000010255	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.948
gpn1	polr1c	ENSPREP00000013283	ENSPREP00000011742	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	RNA polymerase I and III subunit C.	0.852
gpn1	polr2a	ENSPREP00000013283	ENSPREP00000019508	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.909
gpn1	polr2b	ENSPREP00000013283	ENSPREP00000016486	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.945
gpn1	polr2c	ENSPREP00000013283	ENSPREP00000004397	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	Polymerase (RNA) II (DNA directed) polypeptide C.	0.922
gpn1	polr2g	ENSPREP00000013283	ENSPREP00000024621	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	Polymerase (RNA) II (DNA directed) polypeptide G-like.	0.884
gpn1	polr2j	ENSPREP00000013283	ENSPREP00000022590	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	Polymerase (RNA) II (DNA directed) polypeptide J.	0.838
gpn1	rpap2	ENSPREP00000013283	ENSPREP00000011719	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	RNA polymerase II associated protein 2.	0.951
gpn2	gpn1	ENSPREP00000013035	ENSPREP00000013283	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.	0.958

page 1 of 6

Server load: low (26%) [HD]

Permalink

Network

Neighborhood

Experiments

Cooccurrence

Databases

Coexpression

Textmining

Fusion

© STRING Consortium 2025

Credits

Access

Info

About