ENSPREP00000014032 protein (Poecilia reticulata)

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Score

ENSPREP00000014032

Uncharacterized protein. (246 aa)

Predicted Functional Partners:

ENSPREP00000014049

0.942

ENSPREP00000014005

0.939

Herc1

0.926

ENSPREP00000013950

0.900

rnf8

0.628

LOC103461037

0.584

pias4

0.523

nek7

0.510

zfand4

0.506

ND4

0.502

Your Current Organism:

Poecilia reticulata

NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSPREP00000013950	ENSPREP00000014005	ENSPREP00000013950	ENSPREP00000014005	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.900
ENSPREP00000013950	ENSPREP00000014032	ENSPREP00000013950	ENSPREP00000014032	Uncharacterized protein.	Uncharacterized protein.	0.900
ENSPREP00000013950	ENSPREP00000014049	ENSPREP00000013950	ENSPREP00000014049	Uncharacterized protein.	SPRY domain-containing protein.	0.925
ENSPREP00000013950	LOC103461037	ENSPREP00000013950	ENSPREP00000019992	Uncharacterized protein.	RAN binding protein 2.	0.584
ENSPREP00000013950	ND4	ENSPREP00000013950	ENSPREP00000000011	Uncharacterized protein.	NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.502
ENSPREP00000013950	nek7	ENSPREP00000013950	ENSPREP00000018254	Uncharacterized protein.	NIMA-related kinase 7; Belongs to the protein kinase superfamily.	0.510
ENSPREP00000013950	pias4	ENSPREP00000013950	ENSPREP00000012849	Uncharacterized protein.	Protein inhibitor of activated STAT, 4a.	0.523
ENSPREP00000013950	rnf8	ENSPREP00000013950	ENSPREP00000012303	Uncharacterized protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.628
ENSPREP00000013950	zfand4	ENSPREP00000013950	ENSPREP00000028331	Uncharacterized protein.	Zinc finger, AN1-type domain 4.	0.506
ENSPREP00000014005	ENSPREP00000013950	ENSPREP00000014005	ENSPREP00000013950	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.900
ENSPREP00000014005	ENSPREP00000014032	ENSPREP00000014005	ENSPREP00000014032	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.939
ENSPREP00000014005	ENSPREP00000014049	ENSPREP00000014005	ENSPREP00000014049	WD_REPEATS_REGION domain-containing protein.	SPRY domain-containing protein.	0.935
ENSPREP00000014005	Herc1	ENSPREP00000014005	ENSPREP00000014067	WD_REPEATS_REGION domain-containing protein.	Uncharacterized protein.	0.922
ENSPREP00000014005	LOC103461037	ENSPREP00000014005	ENSPREP00000019992	WD_REPEATS_REGION domain-containing protein.	RAN binding protein 2.	0.584
ENSPREP00000014005	ND4	ENSPREP00000014005	ENSPREP00000000011	WD_REPEATS_REGION domain-containing protein.	NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.	0.502
ENSPREP00000014005	nek7	ENSPREP00000014005	ENSPREP00000018254	WD_REPEATS_REGION domain-containing protein.	NIMA-related kinase 7; Belongs to the protein kinase superfamily.	0.510
ENSPREP00000014005	pias4	ENSPREP00000014005	ENSPREP00000012849	WD_REPEATS_REGION domain-containing protein.	Protein inhibitor of activated STAT, 4a.	0.523
ENSPREP00000014005	rnf8	ENSPREP00000014005	ENSPREP00000012303	WD_REPEATS_REGION domain-containing protein.	E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...]	0.628
ENSPREP00000014005	zfand4	ENSPREP00000014005	ENSPREP00000028331	WD_REPEATS_REGION domain-containing protein.	Zinc finger, AN1-type domain 4.	0.506
ENSPREP00000014032	ENSPREP00000013950	ENSPREP00000014032	ENSPREP00000013950	Uncharacterized protein.	Uncharacterized protein.	0.900