STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sirt5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (326 aa)    
Predicted Functional Partners:
LOC103479319
Nicotinamide-nucleotide adenylyltransferase.
   
 0.925
nmnat1
Nicotinamide-nucleotide adenylyltransferase.
   
 0.925
nmnat2
Nicotinamide nucleotide adenylyltransferase 2.
   
 0.925
nadk
NAD kinase a.
  
 
 0.923
LOC103479795
NAD kinase b.
  
 
 0.923
nampt
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
   
 
 0.918
LOC103465472
Nicotinamide phosphoribosyltransferase; Belongs to the NAPRTase family.
   
 
 0.916
LOC103462087
Nicotinamide nucleotide transhydrogenase 2.
   
 
 0.901
LOC103473658
Nicotinamide nucleotide transhydrogenase.
   
 
 0.901
nadk2
NAD kinase 2, mitochondrial; Mitochondrial NAD(+) kinase that phosphorylates NAD(+) to yield NADP(+). Can use both ATP or inorganic polyphosphate as the phosphoryl donor.
     
  0.900
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.