STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000014273Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (408 aa)    
Predicted Functional Partners:
Unc79
Uncharacterized protein.
   
 0.989
ENSPREP00000011136
Uncharacterized protein.
 
  
  0.966
scn1b
Sodium channel, voltage-gated, type I, beta b.
   
 0.951
ENSPREP00000024427
IGv domain-containing protein.
   
 0.951
Scn1a
Uncharacterized protein.
 
     0.949
ENSPREP00000011241
Uncharacterized protein.
 
  
  0.949
LOC103474423
Sodium channel, voltage-gated, type IV, beta a.
    
 0.948
ENSPREP00000011113
Uncharacterized protein.
 
  
 
0.947
ENSPREP00000014343
Uncharacterized protein.
 
  
 
0.947
LOC103475740
Sodium channel, voltage-gated, type IV, beta b.
    
 0.923
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (28%) [HD]