STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (898 aa)    
Predicted Functional Partners:
pick1
Protein interacting with prkca 1.
    
 0.915
CACNG2
Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
   
 0.907
grip1
Glutamate receptor interacting protein 1.
    
 0.839
LOC103467517
Glutamate receptor interacting protein 2a.
    
 0.839
CNIH2
Cornichon family AMPA receptor auxiliary protein 2.
    
 0.811
cnih3
Cornichon family AMPA receptor auxiliary protein 3.
    
 0.811
LOC103476386
Uncharacterized protein.
  
0.747
gria1
Glutamate receptor, ionotropic, AMPA 1a.
  
0.745
LOC103464302
Glutamate receptor interacting protein 2b.
    
 0.728
LOC103471094
Uncharacterized protein.
  
0.726
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.