STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
neil3Nei-like DNA glycosylase 3. (546 aa)    
Predicted Functional Partners:
nthl1
Endonuclease III-like protein 1; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines; Belongs to the Nth/MutY family.
   
  
 0.851
dcakd
Dephospho-CoA kinase domain containing.
  
  
 0.820
coasy
CoA synthase.
  
  
 0.820
MUTYH
Adenine DNA glycosylase; Adenine glycosylase active on G-A mispairs.
  
  
 0.722
LOC103481035
Si:ch211-141o9.10.
     
 0.708
ybey
YbeY metalloendoribonuclease.
  
  
 0.705
poln
Polymerase (DNA directed) nu.
  
  
 0.704
polq
Polymerase (DNA directed), theta.
  
  
 0.704
helq
Helicase, POLQ like.
  
  
 0.704
polg
Polymerase (DNA directed), gamma.
  
  
 0.704
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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