STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mtbpMDM2 binding protein. (745 aa)    
Predicted Functional Partners:
ticrr
Treslin_N domain-containing protein.
   
 0.699
mdm2
MDM2 proto-oncogene.
   
 0.623
recql4
RecQ helicase-like 4.
   
 
 0.604
ccnc
Cyclin C; Belongs to the cyclin family.
   
 0.590
LOC103474795
Uncharacterized protein.
    
 
 0.556
cdc45
CDC45 cell division cycle 45 homolog (S. cerevisiae).
   
 
 0.540
clg11h1orf109
C19h1orf109 homolog (H. sapiens).
      
 0.522
dbf4
DBF4 zinc finger.
   
 0.508
topbp1
DNA topoisomerase II binding protein 1.
   
 0.490
tbpl2
Uncharacterized protein.
    
 0.479
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.