STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ctsoCathepsin O; Belongs to the peptidase C1 family. (327 aa)    
Predicted Functional Partners:
bcl2
BCL2 apoptosis regulator b.
     
 0.901
birc2
Baculoviral IAP repeat containing 2.
     
 0.659
LOC103481969
Baculoviral IAP repeat containing 5a.
     
 0.659
LOC103467341
Baculoviral IAP repeat containing 5b.
     
 0.659
LOC103466909
BH4_2 domain-containing protein.
     
 0.656
BCL2L1
BCL2 like 1.
     
 0.656
lgmn
Legumain.
   
 
 0.602
tdo2
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
  
 0.588
LOC103472913
Uncharacterized protein.
   
  
 0.552
espl1
Extra spindle pole bodies like 1, separase.
      
 0.549
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.