STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gstk1Glutathione S-transferase kappa. (228 aa)    
Predicted Functional Partners:
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
   
 
 0.934
LOC103477101
Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.
   
 0.913
LOC103462617
Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.
   
 0.911
gss
Glutathione synthetase.
   
 
 0.910
LOC103477226
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
     
 0.908
txndc12
Thioredoxin domain containing 12 (endoplasmic reticulum).
    
 0.902
ENSPREP00000000999
Microsomal glutathione S-transferase 2.
   
 0.871
gpx7
Glutathione peroxidase; Belongs to the glutathione peroxidase family.
   
 0.852
mgst1
Microsomal glutathione S-transferase 1.2.
   
 
 0.775
LOC103476790
Uncharacterized protein.
   
 
 0.773
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.