STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sppl3Signal peptide peptidase 3. (383 aa)    
Predicted Functional Partners:
st3gal4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family.
      
 0.637
nagpa
N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase.
      
 0.542
apip
Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Functions in the methionine salvage pathway. May play a role in apoptosis.
      
 0.536
SLC35A4
Solute carrier family 35 member A4.
   
  
 0.480
slc35a1
Solute carrier family 35 member A1.
   
  
 0.480
fam98a
Family with sequence similarity 98 member A.
      
 0.471
ttc19
Tetratricopeptide repeat domain 19.
   
  
 0.469
LOC103464869
Nodal modulator.
      
 0.440
PIGY
Phosphatidylinositol glycan anchor biosynthesis class Y.
      
 0.440
sec63
SEC63 homolog, protein translocation regulator.
   
 
 0.431
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.