STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSPREP00000015380TNFR-Cys domain-containing protein. (279 aa)    
Predicted Functional Partners:
LOC103462560
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
   
 0.966
ENSPREP00000002926
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.963
tnfsf11
TNF superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.759
LOC103471589
CD40 ligand; Belongs to the tumor necrosis factor family.
   
 0.740
LOC103477745
Tumor necrosis factor b (TNF superfamily, member 2).
   
 0.683
ENSPREP00000019119
Ig-like domain-containing protein.
   
 0.672
ENSPREP00000029074
Tumor necrosis factor a (TNF superfamily, member 2).
   
 0.530
tnfrsf11a
Tumor necrosis factor receptor superfamily, member 11a, NFKB activator.
   
 0.498
tnfrsf1a
Tumor necrosis factor receptor superfamily, member 1a.
  
  
 0.494
tnfsf12
TNF superfamily member 12; Belongs to the tumor necrosis factor family.
   
 
 0.426
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.