STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Kcne4Potassium voltage-gated channel, Isk-related family, member 4. (185 aa)    
Predicted Functional Partners:
kcnq1
Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.
    
 0.654
ENSPREP00000028578
Ion_trans domain-containing protein; Belongs to the potassium channel family.
    
 0.654
lipt2
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
      
 0.549
prim2
DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands.
      
 0.540
tulp4
TUB like protein 4a; Belongs to the TUB family.
      
 0.470
LOC103458365
TUB like protein 4b; Belongs to the TUB family.
      
 0.470
ENSPREP00000024223
Uncharacterized protein.
      
 0.468
KCNH7
Potassium voltage-gated channel subfamily H member 7.
     
 0.451
kcnh6
Potassium voltage-gated channel, subfamily H (eag-related), member 6a.
     
 0.451
LOC103482352
Uncharacterized protein.
     
 0.451
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.