STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC103472446Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide; Belongs to the 14-3-3 family. (250 aa)    
Predicted Functional Partners:
CDC25B
Cell division cycle 25B.
    
 0.975
yap1
Yes-associated protein 1.
    
 0.706
metrn
Meteorin, glial cell differentiation regulator.
    
 0.700
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
 0.675
prkdc
Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family.
    
 0.675
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.675
LOC103469576
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.675
tsc2
TSC complex subunit 2.
    
 0.657
hmbs
Hydroxymethylbilane synthase a.
    
 
 0.650
pgk1
Phosphoglycerate kinase.
   
 
 0.649
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.