STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DTX1Deltex E3 ubiquitin ligase 1. (642 aa)    
Predicted Functional Partners:
LOC103473440
Notch receptor 1a.
    
 0.808
notch1
Notch receptor 1b.
    
 0.808
LOC103463625
Notch receptor 2.
    
 0.776
LOC103468742
Notch receptor 3.
    
 0.753
itch
E3 ubiquitin-protein ligase.
    
 0.618
wwp2
E3 ubiquitin-protein ligase.
    
 0.618
wwp1
WW domain containing E3 ubiquitin protein ligase 1.
    
 0.618
LOC103464828
E3 ubiquitin-protein ligase.
    
 0.618
rps27a
Ribosomal protein S27a.
    
  0.557
mtx3
Metaxin.
      
 0.525
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.